When a young boy disappears from his home in St. Louis, the team examines a similar cold case for clues.
House and the team take on the case of a struggling artist with an undiagnosed illness that's distorting his perception and threatening his career; House continues to have a private investigator dig up dirt on everyone on his team.
Extensive plastic surgery hides the identity of a body whose parts were found near an airport.
Jane and Maura investigate a modern witch hunt; Frankie's old girlfriend returns with a surprise.
Kitty finds herself torn between two men; Justin's new job is more than he bargained for; Sarah and Joe face their greatest challenge yet as parents.