When Alan's night terrors return, he asks his new, attractive secretary, Melissa, if she would sleep with him to keep him from hurting himself.
An unexpected incident threatens to disrupt Carla and Turk's wedding preparations. J.D. realizes Jamie is a drama queen. Dr. Cox is forced to teach a course on doctor-patient communication.
Sabrina (Melissa Joan Hart) invites her fussy grandmother (Shirley Jones) to visit, despite protests from Hilda and Zelda (Caroline Rhea, Beth Broderick).
Eli adjusts to his new position at the law firm; Maggie becomes lead counsel on a case with Eli, and the role reversal brings them closer together; Taylor tries to reunite with Eli through a live performance by George Michael.
Chris (Darlene Vogel) is plagued by guilt and doubt after failing to apprehend a trio of jewelry store robbers.