On his first day as an intern, an idealistic Dr. Devon Pravesh faces the harsh realities of medical care; resident Conrad Hawkins teaches him unconventional methods for treating patients.
A blackout requires the staff to treat their patients without the help of any technology; Bell orders the staff to stop accepting new patients; Conrad and Devon go against the mandate to help a child; Mina and Austin must perform heart surgery.
Devon's doubts about his relationship reach a peak as his friends and family gather for his big wedding day.
Nic and Conrad diagnose a happy husband and wife who are both admitted to the hospital with mysterious symptoms; Bell and Marshall butt heads on a work trip; A.J. turns down a request from Bell despite Mina's forewarning.
Conrad's plans for a heart transplant patient are derailed; Conrad risks his job to rectify the situation; after a file goes missing, Nic grows suspicious of one of the doctors.