Kate and Guddi meet Hilda, a fashion influencer suffering from fibroids who confronts her debilitating condition, as well as grandmother Trudi, who is struggling with a frozen shoulder.

Kate meets Rozi, a doting grandmother to 23 grandchildren, who tries to understand why Covid-19 hit her so hard, as well as Adrian, whose prostate has enlarged so much that he is in agony.

Kate and Guddi meet Judith, a singer who has been delaying treatment of a thyroid nodule for fear it may damage her singing voice, as well as Melina, whose love for good food has been curtailed because of agonising gallstone attacks.

Kate and Dr Guddi meet Tina, whose adventurous lifestyle has ground to a halt because of a spine problem, and Annabelle, who was pregnant when she found out she had breast cancer.

Kate and Guddi meet Miriam, a young woman who has endured years of pain and fatigue because of endometriosis, and John, who's recently been diagnosed with kidney stones, a common but painful condition.

Paul is a young man with a young family. He's always led an active life until two years ago, when he suffered a stroke. Janet recently turned 70 and was looking forward to some sailing adventures with her husband when their world was turned upside down. Janet noticed a strong pain in her back and blood in her stool. After a number of tests, a tumour was discovered in her bowel.