Arnold "the Brain" Rothstein schooled the founders of the American Mafia in the ways of organized crime in the 1920s; infamous for fixing the 1919 Baseball World Series, he was the criminal genius behind a bootleg empire.

Murder, Inc. head Albert Anastasia oversees the American Mafia's most violent period in history, but eventually would outlive his usefulness.

Under the disguise of mental illness Vincent Gigante evaded the authorities and rose to become the most powerful mobster in New York. When FBI realised their mistake they would stop at nothing to take him down. But would he escape one last time?

Known as the "Last Don," Joe Massino crushes anyone who goes against the mafia code of "omertà," but when the FBI takes him down, Massino turns state's evidence and takes everyone down with him.

In the 1980's and 90's the mafia controls the New York criminal underworld; by the early 200's evidence surfaces that the mob has gone much further and has people inside the NYPD.

In the lawless days of Prohibition America, one gangster, Dutch Schultz, stands out as the black sheep; when Dutch threatens to kill a state prosecutor, the mob can't risk the fallout, so they send Dutch a special message: a body full of lead.