FBI Agent Kate Moretti recruits her former neuroscience professor to help out on a case involving the death of a pharmaceutical executive; Daniel's hallucinations threaten to derail the case.

Moretti and Pierce investigate a murder in which the suspect has a condition that makes him unable to recognize faces; Moretti is attracted to a new professor.

Pierce and Moretti search for clues when a serial killer from 1986 resurfaces; Moretti's father offers her advice on a case.

Pierce tries to crack a code left in a newspaper by someone who may be connected to a murder, but time is not on his side, as another victim's life may be in danger.

Pierce and Moretti investigate the murder of a young man who claimed to be hearing the word of God; the university gives Pierce an award for his research.

Pierce is asked to help investigate the murder of a therapist; Moretti spends time with professor Hathaway; Dean Haley tries to get an alumnus' widow to fund a new building.