George Williams and his daughter Anna run Chevin Chase Veterinary Practise in the market town of Oxley. Anna’s hands are full with three children, another on the way, a struggling practice and a wedding to organize. Sparks fly when her sister Sarah, complete with designer lifestyle, swans up from London for the first time in years.

When Sarah refuses to perform a simple operation, her sister Anna accuses her of “running away” from her responsibilities yet again! What is it that Sarah is actually running from? Can she prove her sister wrong, and come through for her family and the practice, or will the ghosts from her past make it impossible for her to stay?

As Sarah attempts to propel Chevin Chase into the 21st century, she is distracted by the attentions of an old flame. Meanwhile Anna, busy organizing Imogen’s christening, is furious with her domineering new step mother – as she insensitively ‘clears out’ their late mother’s possessions. As if this wasn’t enough to deal with, Anna also makes a shock discovery that changes her life for ever.

The one thing Tom Bedford needs is good night’s sleep, and that’s the one thing he’s not going to get! With a new born baby, an unwelcome visitor, and a dark secret, Tom is struggling to keep his head above water. Will he meet Fiona’s demands, or will Anna discover the shocking truth?

Frustrated with being stuck in Yorkshire for her honeymoon, a chance conversation causes Claudie to realize she has even more pressing reasons for leaving the country, leading to a fiery family showdown. In the practice, Fiona struggles to keep her hold over Tom, and Sarah has a respite from spaying cats to spend an afternoon with old flame Adrian Huby.

Chaos reigns at Chevin Chase as decorators and gardeners battle for space with dogs and rabbits in preparation for the relaunch. The vets are distracted however, as Sarah receives some news from her ex-boyfriend, and Rick reaches the end of his tether in his marriage to Deborah. Much to his surprise, Matt finds himself giving advice on birds and bees.