Months after having a kid, Tim, a middle-school science teacher, books the cabin to spice up his sex life with his wife Sandy, but when things take an unexpected turn, Tim finds himself way over his head in a criminal conspiracy.

Devout mother Jill is annoyed that her son Ethan has brought his atheist fiancée Lynn to the cabin for a family getaway.

Phyllis and her husband's weekend retreat with his boss and the boss' much younger wife becomes unbearable for Phyllis, until she finds an unlikely escape by helping stranger Marcia run away from a plural marriage.

Christy heads up to the mountains to try and bond with her new boyfriend Paul and his 8-year-old daughter, but she self-medicates because of her anxiety and ends up revealing some skeletons in her closet.

Hopeful medical researcher Laurie visits the cabin with her Alzheimer's patient Edgar in an attempt to re-create his past life and help him recapture some of his memories.

Federal agent Trina books the mountain cabin to protect valuable witness Blake, but Blake has his own ideas on how to escape the people who are after him.