When an experimental government weapon falls into the hands of a mysterious group of Russians with questionable intentions, it's up to CIA agent Greg Larson (Billy Zabka) to retrieve top-secret property -- a giant mutant snake. But, when the Russians lose control of the python, the situation gets out of control quickly, and many lives are put in jeopardy. The snake wanders near the home of retired baseball player Dwight Stoddard (Dana Ashbrook), who then tries to save the day.