Drifter Jess Harper arrives in Laramie searching for a man, but gunfire sends him out into the countryside, where he meets rancher Slim Sherman and his brother, Andy.

Martha Chambers takes refuge from vengeful Indians at the Sherman ranch after she kills the son of a Pawnee chief in a moment of blind terror.

Jess takes on an undercover job for the sheriff, acting as a guide for an outlaw who's searching for money stolen in an earlier robbery.

Slim and Jess capture an outlaw and his partner, but find the tables turned when the outlaw's gang breaks the pair out of jail during the trial.

Wyoming Territory has become the winter battleground for the warring Sioux and Cheyenne, forcing Slim and Jess to close the ranch and relay station.

After a drought and the ending of the stage line, Slim and Jess must join a cattle drive run by a stranger who at first seems impressive, but soon their suspicions are aroused.