The "don't try this at home" warning seen on some TV shows doesn't apply to this series, which encourages the discovery of scientific concepts through experiments that viewers can reproduce in their own homes. Science teacher Steve Spangler hosts the show, providing step-by-step demonstrations of the DIY experiments that help explain scientific principles. Among the experiments presented is one that gained Spangler fame, in which he showed what happens when a mint candy is dropped into a bottle of diet soda. On the show, he explains the "why" and "how" behind the experiment and what cause the soda to react with the candy.