Abruzzi, Sucre and C-Note run on their own; Michael and Lincoln plan another breakout; Bellick and Warden Pope have to answer to their peers regarding the prison escape; Tweener hitches a ride with the college crowd.
T-Bag tries to track down missing Mrs. Hollander; Sucre's escape plane faces deadly turbulence; the tables turn on Bellick upon his return to Fox River; Michael and Lincoln are taken into custody and transported back to Fox River.
The Five-0 must once again engage in the twisted mind games of serial killer Dr. Madison Gray when she arrives at the HPD covered in blood that matches Alicia Brown's.