Elizabeth visits the Middle East to finalize a deal to bring U.S. troops home; a woman's life is threatened by rumors of a romance with one of Elizabeth's staffers; Henry provides relationship advice to Elizabeth's brother.
While Elizabeth is away on a retreat thinking about her presidential campaign, her staff tries to secure an international agreement to protect citizens who have been displaced due to global warming; the staff works to contain a measles outbreak.
When Venezuela's president and his immediate successors die in an earthquake, Elizabeth must stop the late president's son from taking over, and she must negotiate the release of some international aid workers that he arrested.