Holmes investigates himself when he becomes a suspect in a murder that took place during the height of his addiction; clues make Holmes question his innocence.
Will's latest case - which could net the firm millions - hangs in the balance as Alicia navigates Louis Canning's attempts to delay a deposition crucial to Will's argument. Michael J Fox and T.R. Knight guest star.
The doctors launch an investigation after Betsey's second emergency room visit; Naomi makes a life-changing decision; Amelia continues to struggle with sobriety.