Detective Sherlock Holmes investigates a home invasion that led to murder.
When a man is shot and killed while entering his apartment, Sherlock investigates; Watson goes to dinner with her ex-boyfriend.
Sherlock and Watson investigate a child abduction case involving a serial killer known as "The Balloon Man."
Holmes consults on a case involving a Wall Street executive who seems to have died from a heroin overdose; Holmes encourages Watson to start dating again.
Sherlock tracks the person who has been killing terminal patients at a hospital but making it look like they died of natural causes; more information on Watson's decision to end her surgical career is revealed.
After a small plane crashes, Sherlock tries to prove that one of the victims was already dead before the plane went down; Watson thinks Sherlock should get together with his elusive father.
Jonny Lee Miller
Sherlock Holmes
Lucy Liu
Dr. Joan Watson
Aidan Quinn
Captain Thomas Gregson
Jon Michael Hill
Detective Marcus Bell
Nelsan Ellis
Shinwell Johnson