In the Series Premiere, John gets a job writing comedy for demanding and infantile game show host Lou Cannon, which turns out to be less glamorous than expected. Meanwhile John’s roommate, Jane, attempts to prove to an ex that she isn’t “psycho”; and his other roommate, Motif, struggles to write a joke with a killer punchline.

When John starts dating a doula, he faces his fear of childbirth; John talks to Lou about his provocative behavior.

When John uses his late neighbor Lapidus' jokes for Lou's monologue, he finds himself willing to rob the man's grave to get more of his material and prove his worth at work.

Mulaney tries to ascertain why Jane doesn't get along with any of the girls he dates; fixating on his own death, Lou asks John for help planning a dignified demise.

When John's very religious parents visit, he must lie about how often he goes to church; Jane goes on the pill to impress a guy.

John and Motif try to sign up for a USO Comedy Tour after Jane starts dating a marine; Lou believes war and improv are both difficult.