Anthony is shot while interviewing a witness; Erin enlists his archenemy, Danny, to investigate the case; Jamie and Eddie get in the middle of a standoff between a police lieutenant and a developmentally disabled man posing as an officer.
An old army buddy and fellow surgeon visits Conrad at the hospital; the team is put to the test when they have to save the life of an uninsured and undocumented patient; Dr. Bell experiments with a new medication for his tremor.
Michael hunts Anson through Miami, racing against the clock; Fiona is taken into custody and interrogated by an old nemesis.
Frank learns the dean of Rosegrave Preparatory School had a connection to his mother; Joe and Biff continue to investigate the scrap of fabric from the warehouse; Mrs. Khan makes a play for the missing piece of The Eye by enlisting the Tall Man.