Several of the doctors compete to be the new face of Seattle Grace; April brings an emergency case to the hospital; Alex and Jackson work with a transgender teen couple; new policies test the patience of the staff.
Castle and Beckett investigate the murder of an Internet celebrity; when pictures of the crime scene show up on a photo sharing website, the investigators worry the killer may strike again.
The team investigates when the body of a music producer turns up on a yacht; Rosewood faces a startling revelation about Tawnya.