Holmes consults on a case involving a Wall Street executive who seems to have died from a heroin overdose; Holmes encourages Watson to start dating again.
A NATO ally carries out a state-sponsored assassination attempt against one of its own citizens, who is also a U.S. resident and old friend of Elizabeth's; Alison starts dating the son of one of Elizabeth's political rivals.
A feud between a famous author (Robert Vaughn) and his sixth wife, Charmaine (Marcia Cross), turns into a criminal case when Charmaine is faced with allegations of abuse; Barba winds up dealing with family drama of his own.
Holmes and Watson search for a civil contractor who leaked classified information, but their lives are disrupted by a group of cyberactivists determined to protect the contractor; Joan signs up for an online dating service.
Alicia must once again aid Colin Sweeney when a sexual misconduct claim derails his attempt to win back control of his company. Bebe Neuwirth and Morena Baccarin guest star.