Kelsey dates a seemingly perfect guy, but Liza and Lauren think it's too soon. At a party of doctors, Josh puts his relationship with Liza under the microscope.
Secretary of State McCord agrees to host a holiday party to persuade senators about a landmine treaty; Henry looks for evidence that the senate majority leader exchanged information with the Russians.
As the team gathers to mourn the loss of someone dear, Max and Helen realize the extent to which New Amsterdam has changed since they left; Bloom struggles with a big decision; Reynolds decides to take his concerns for his patients to a new level.
The team must protect a scientist who has developed a deadly technology that, in the wrong hands, could have devastating consequences to mankind; Ryan and Shelby stumble on something of Alex's that signals a possible change in her personal life.
Jocelyn battles the adversary responsible for the bomb explosion that changed her life forever; the team infiltrates an illegal, underground operation that has deadly consequences.