After being diagnosed with melanoma, Cathy decides to build a pool in her backyard, much to the chagrin of her older curmudgeonly neighbor, Marlene. Cathy’s son, Adam, plays pranks on her while her husband Paul tries to get back in her good graces. Cathy also tries to reconnect with her willfully homeless brother Sean, and devises a weight-loss plan for Andrea, one of her summer school students.

Cathy learns from Dr. Todd just how little time she has left, and for the first time in her life, starts to appreciate her body. Paul tries to make sense of his wife's request to live apart for the summer by signing up for couples therapy. Adam, desperate to get away from his "crazy" mom, attempts to sneak off to soccer camp without her knowing.

When Cathy's attempt to connect to the people closest to her fails, she signs up for a well-meaning but overbearing cancer support group. Adam rebuffs Cathy's attempts to connect with him, so she decides to put together a dinner party with Andrea, Sean and Daphne. Meanwhile, Paul tries to win back his wife's love with an elaborately romantic gesture. Marlene discovers Cathy's cancer secret in a most unusual way.

Cathy, eager to try on a carefree, impulsive persona, drains her 401K, buys a convertible and imagines what life would be like if she were Dr. Todd's girlfriend. At his therapist's urging, Paul reignites his passion for rugby. Sean goes to great lengths to knock out a tooth without the help of a dentist. Meanwhile, Adam gets caught stealing and is surprised when Marlene comes to his rescue, until he finds out there are strings attached.

Cathy meets someone new to feel sexy again. Meanwhile, Cathy's eccentric brother Sean tries to keep his building and Adam is caught while watching pornography.

Cathy needs a lump on her butt removed and someone to pick her up after surgery. She asks Marlene, who becomes disoriented - so Lenny picks up Cathy instead. Sean moves into Cathy's backyard because he got beat up on the streets. Paul and Adam win the local bathtub races. The event brings Cathy and Paul back together, but at the point of reconciliation, Paul confesses to an indiscretion with Tina and Cathy rejects the reunion. Meanwhile, Andrea breaks into the school and destroys the mural Lenny painted.