Alixandrée Antoine

Derek and the attendings go out to celebrate when he gets the grant he needs for his clinical trial; Meredith and Alex must fend for themselves during the night shift.

Owen puts the residents through a rigorous trauma certification drill; Cristina is left alone to monitor an ill lung transplant patient.

As part of their training, Seattle Grace's residents are put in charge; the attending surgeons compete for a million-dollar grant.

Unsettling news motivates Derek and Meredith to take preventive steps for their children's future; Syrian doctors come to the hospital for a crash course in basic surgical skills; April decides to tell Matthew the truth.

After learning about Richard's drinking problem, Derek confronts him; Izzie returns, hoping to reconcile with Alex; tensions run high for Teddy, Cristina and Owen in the aftermath of Cristina's startling confession.

The crash of a small plane results in multiple casualties -- and brings back terrible memories, particularly for Meredith and Arizona; friction between Amelia and Owen becomes uncomfortable at work.