Moe Irvin

Meredith Grey and four other first-year surgical interns try to balance life and work at Seattle Grace Hospital.

An exhausted Meredith thinks she may have made a mistake during surgery, which could jeopardize her career. Meanwhile Izzie's plan to throw a party for her new boyfriend goes completely awry, and Alex deals with a patient who is addicted to painkillers.

Meredith's fears that she is in for a bad day are realized when a medical case arrives at Seattle Grace that threatens the lives of everyone in the O.R.

One person's fight to live affects everyone at Seattle Grace, in the dramatic conclusion to "Grey’s Anatomy's" three-episode story arc.

George's skill level dazzles the new interns; Meredith halfheartedly helps Lexie with her first emergency patient.

Alex gains the trust of Annie, a nervous patient with an extraordinarily large tumor, only to humiliate himself in front of her later. Meanwhile Derek chooses Meredith to assist with an elderly Parkinson's patient who may need surgery -- but Bailey disapproves of their relationship and is determined to make Meredith suffer -- and tensions escalate between Burke and Shepherd.