Mistaken identity abounds as Jess inadvertently captures the attention of a beer delivery guy (guest star Josh Gad) and then pretends to be someone else when a handsome stranger (guest star David Walton) thinks she is his blind date. Then, a regular at Nick’s bar (guest star Raymond J. Barry) claims to be Nick from the future, and Winston’s disapproving mother (guest star Anna Maria Horsford) comes to visit, all the while maintaining her hatred of Schmidt.
Though X-Files has been shut down, reassigned Mulder investigates a a tip from his mentor, leading him to a communications center in Puerto Rico, looking for evidence of a close encounter.
The doctors put together a fundraising gala; Bailey must face several difficult patients; Shane and Stephanie take care of the busy ER on their own; Alex opens up to Jo.
The members of Oceanic 6 discover how to get back to the island, but not all of them want to return.
The group faces a threat when they discover a new refugee is a spy working for Sentinel Services; Reed visits his estranged father and learns secrets that could prove useful.