Jeff Perry

The race for chief heats up after a new competitor enters the fray, tensions escalate between Izzie and George, and Callie must reveal a big secret. Meanwhile, Derek treats a patient near and dear to him, while Alex continues his work with Jane Doe.

After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part One of a two-part episode.

Addison takes temporary leave from Seattle Grace and makes a road trip to Los Angeles in order to visit some old friends from medical school. As Meredith continues to bond with her stepmother, Susan, Cristina reluctantly plans her wedding with the assistance of her mother, Helen, and Burke's mother, Mama Jane. Meanwhile, Derek must perform emergency surgery on Ava/Jane Doe, as Alex continues his unfailing bedside manner with her.

Addison gets a job offer away from Seattle Grace; Burke continues to have reservations about marrying Cristina; Susan returns to the hospital after feeling ill following the surgery.

After a successful operation on his heart, George's father undergoes surgery for his cancer, Thatcher Grey visits Seattle Grace in order to see his new granddaughter, and Meredith discovers that Derek has trouble sleeping soundly. This is Part Two of a two-part episode.