John O'Brien

Chandler and Monica leave for their honeymoon as Rachel prepares to tell Ross he's the father of her baby. Monica and Chandler become jealous of another honeymooning couple who get bumped to first class on the plane.

Cristina’s encounter with a former nurse, now a patient at Seattle Grace, changes her forever; Derek and Meredith treat a construction worker who has miraculously survived an injury but is now faced with tough decisions about his future; and a patient recognizes Izzie from a lingerie ad, which makes her the subject of hospital gossip.

The residents of Seattle Grace and Mercy West fight for surgeries as day one of the hospital merger begins.

Alex gains the trust of Annie, a nervous patient with an extraordinarily large tumor, only to humiliate himself in front of her later. Meanwhile Derek chooses Meredith to assist with an elderly Parkinson’s patient who may need surgery -- but Bailey disapproves of their relationship and is determined to make Meredith suffer -- and tensions escalate between Burke and Shepherd.

Meredith and Lexie's father returns to Seattle Grace with stomach pains and a new girlfriend; Alex butts heads with the new OB; Mark bribes Jackson for information on Lexie.

Evelyn buys Alan a new sports car causing Charlie to claim that his brother has sold his soul to the Devil. The next day, Evelyn extracts payment by insisting that Alan go on a blind, double date with her, her new beau and his daughter.