Lorena Diaz

A family of victims from a house fire are rushed to Gaffney. Lenox fights to save two sisters injured in an all-night rave turned tragedy. Tensions mount between Goodwin and Abrams over difficult staffing changes.

Rhodes and Zanetti race to save a member of Firehouse 51, April's brother struggles during his first day at the hospital, and a woman saved from a burning building leads to a bigger mystery.

A car crash at the Chicago Marathon leaves victims in critical condition, and April and her medical resident brother must perform an operation in the field. An 8-year-old girl experiences sudden hearing loss, and Dr Choi treats a malnourished woman.

The Emergency Room's charge nurse is arrested for refusing to run a blood test on a DUI. Dr Halstead seeks legal advice. Dr Manning has a difficult case.

Dr Rhodes begins his cardiothoracic surgery fellowship, but gets off on the wrong foot with his new boss, Dr Latham. Meanwhile, Dr Choi begins his life as chief resident, and Sarah is caught off-guard by Dr Charles.

The team find a surprising connection between two elderly patients presenting similar symptoms. Dr Manning loses her wedding ring.