On his first day as an intern, an idealistic Dr Devon Pravesh faces the harsh realities of medical care. Resident Conrad Hawkins teaches him unconventional methods for treating patients.
Much to Bell's dismay, Nic and Conrad decide to admit a homeless Jane Doe, whom they suspect was dumped off by another hospital during Chastain's big Charity Ball.
Mina goes out of her way to help a young man from her neighbourhood who almost mugged her. Nic offers her assistance and discovers a secret that Mina has been keeping behind closed doors.
An attack by cybercriminals sends the hospital into a tailspin and Kit must decide whether to pay the ransom; Conrad works on balancing life as a new dad; Devon and Leela debate taking the next step in their relationship.
The wait is over as Conrad and Nic welcome the arrival of their baby girl; Raptor's life begins to fall apart and he is forced to turn to Cain for help; Devon and Bell work together on a complicated surgery that may allow them to save multiple lives.