As the team gathers to mourn the loss of someone dear, Max and Helen realise the extent to which New Amsterdam has changed since they left. Bloom struggles with a big decision. Reynolds decides to take his concerns for his patients to a new level.
A journalist visits New Amsterdam to shadow Max and learn about the hospital. Bloom and Reynolds have a major disagreement after she makes a call against protocol and Kapoor deals with issues from his past.
A patient's treatment plan takes an unexpected turn when Max gets overly invested. Meanwhile, Reynolds celebrates his birthday with some help from the hospital and Kapoor grapples with a case that hits close to home.
Max takes a chance on a new assistant and goes toe-to-toe with the board on a new plan. Iggy struggles to figure out what is causing a unit-wide illness. Kapoor receives some shocking news.
Max continues to work to solve underlying problems within the hospital despite his continuing struggles with treatment. Meanwhile, Reynolds makes the choice to do a costly surgery to determine an elusive diagnosis and Bloom must face her personal demons head-on.