Meredith and Derek get one last shot at success in their clinical trial; the surgeons work together to free a boy from a block of cement; Izzie helps Alex care for Rebecca; Lexie uncovers critical information about George's status as an intern.
An international incident prompts the staff to rewrite the president's address on the eve of his inauguration.
The president greenlights a raid on homegrown terrorists in Idaho; the staff tries to negotiate more debates with Bartlet's Republican rival.
When a patient from a distant town needs surgery, Scott is determined to help her; Jordan takes a creative approach to helping a wounded veteran; Drew finds support from an unusual patient; T.C. goes on a daring rescue mission in Syria.