When a judge known for serving harsh sentences to juveniles is murdered, the team looks into his lengthy list of cases in the hunt for his killer; Kristin faces family hurdles while resettling with her teenage daughter in New York City.
Tommy must decide how to deploy the LAPD's resources when a climate change protest brings riots and a bomb threat at the same time as a mudslide shuts down a major freeway.
Max and Sharpe wake up to a new, more personal dynamic; Iggy calls upon an old contact to help with an explosive situation; Bloom begins a tricky dynamic with her new Emergency Department residents; Reynolds finds himself in an awkward position.
It's National HIV Testing Day and Max has offered free care to all HIV+ patients who come to New Amsterdam; Bloom and Reynolds butt heads over their opposing bedside manners; Iggy eagerly awaits the return of a friend; Sharpe makes a discovery.
With the hospital on lockdown after the Rikers patients escape, Sharpe and Max find themselves in a situation that could cost them their lives; Bloom must put aside her pain to help a patient; Iggy is forced to face his marriage's issues.