An infection threatens Crockett's risky liver transplant. Maggie and Charles help a struggling burn unit nurse. Goodwin is forced to make a tough decision about Bert's future.
Ripley and Charles treat a high-risk prisoner who may have dementia. Archer and Sean clash when a resident from Margo's facility lands in the E.D. Crockett receives shocking news.
Ripley struggles to keep Sully's diagnosis a secret when the latter's pregnant girlfriend comes to Med for help. Loren works to earn a spot in Med's trauma fellowship. Charles and a medical student treat a bipolar artist.
Maggie's budding romance takes flight. After a woman's shocking suicide attempt, Charles searches for answers. Hannah works to diagnose a patient who's new to the city and appears with mysterious symptoms.
Ripley and Charles treat members of a cult. Zola's suspension takes an unexpected toll on Crockett. Dr. Abrams' 5-month-old son lands in the E.D. under questionable circumstances.