The interns take their first-year medical exams; the residents attend to three injured mountain-climbers; Callie's suspicions of George and Izzie grow; Cristina struggles to write her wedding vows.
Meredith's friends and fellow doctors work to save her life after her near-drowning; Izzie gathers her courage to perform surgery at the site of the ferry accident.
Derek and Meredith get ready for their wedding; college students injured in a car accident are admitted to the ER; Izzie starts experiencing familiar symptoms.
Voight's new Internal Affairs handler proves to be suspicious of his actions; Voight must work with his former partner from the Gang Unit; Halsted enlists Jin to help him gather more information on Lonnie Rodiger; Olinsky takes Ruzek down a peg.
Tori and her friends are hired to replace the band at a child's birthday party; André must prove himself to a record producer.