Holmes investigates himself when he becomes a suspect in a murder that took place during the height of his addiction, clues make Holmes question his innocence.
Following an art restorer's mysterious death, Ichabod and Katrina are reminded of a friend (Michelle Trachtenberg) from their past; a visitor at the police precinct shocks Abbie.
Following President Ostrov's death, President Dalton and Elizabeth fear an impending power grab within the Russian government; Jay forms a plan to combat Russian propaganda.
Elsbeth and Alicia put their fight on hold when they both have clients facing economic espionage charges; Diane battles her former partners over office space.
Jamie finds himself under investigation, while Danny and Baez investigate the suspicious death of a hotel employee.