The chief makes a decision that shocks everyone at Seattle Grace; Owen and Cristina attempt to find normalcy; April struggles in her new role; the 5th-year residents receive their first solo surgery assignments.
Eddie takes Alison to a modern reworking of Romeo and Juliet for their first anniversary. Jessica is called up for jury duty. Emery and Evan are weighed down by the responsibilities of raising a digital pet.
The team links a bizarre crime scene at Arlington National Cemetery to a string of attacks on homeless veterans.
Sheldon agrees to help Missy with her maths homework. Georgie joins a bible study group to get closer to Veronica.
In the first part of a two-part episode, the team begin a joint investigation with the FBI regarding a serial killer who has reappeared after 27 years of silence.