Meredith and Cristina bicker about their careers; Bailey talks to Ben about him moving back to Seattle; Shane puts himself in a risky situation; Derek receives a life-changing phone call.
April's visiting sisters get on her nerves; when Matthew and Jackson witness an accident, they must work together; Callie and Arizona work on their relationship.
The murder of a teenage boy leads to a dubious high school principal, a terrifying legend, and a mysterious secret society.
Grace has developed a worrying obsession with the aliens, and it threatens Kit's newfound chance at a happy ending when things turn violent. Meanwhile, a deadly new inmate threatens Sister Jude's chance of release from Briarcliff.
Sean and Christian settle into their new practice in Beverly Hills and struggle to build it from the ground up. New opportunities arise after they meet a slick Hollywood publicist.