April becomes overwhelmed as she tries to balance home and career responsibilities, Leo has suspicions about April's motives, and Brenna forms a surprising bond with a popular girl at school.
April still struggles to tell Dominic about her cancer, but she opens up about the skeletons in the Carver family closet.
Chris tries to convince Reagan to have another baby. Meanwhile, Ava ends up disappointed when she joins her idol Yvonne's mentorship program.
With the start of her treatment looming, April finds herself with Leo on an eye-opening joyride. Brenna's uncertain relationship with Kiernan causes tension with Greer.
April learns about fertility options prior to starting chemotherapy, and seeks advice from her support group about breaking the news. George tries to help Sara cope.