A killer with a number of identities leads the authorities on a baffling chase through the South; the Behavioural Analysis Unit has a tricky job on their hands as they attempt to profile the man beneath the rapidly changing exterior.
With Lincoln's execution now just a day away, Michael looks for a way to get him out of solitary confinement in time for an escape. Meanwhile, Veronica comes out of hiding and gains an ally.
Miranda Bailey brings a kidney transplant patient to Los Angeles, meanwhile the consequences of Addison's emotional affair with Noah catch up with her.
Willis, Noa and Elliott rush to the scene of a fire at a haunted theatre, where Dr Nolan and her boyfriend's son are trapped.
Denny and Carl head to Virginia to defend a corrections officer accused of murder after he shot a death row inmate when his lethal injection went awry.