Meredith's fears that she is in for a bad day are realized when a medical case arrives at Seattle Grace that threatens the lives of everyone in the O.R.
Despite the best efforts of the Seattle Grace staff, the code black situation escalates.
The BAU team begin to track a family in Alabama who are working together to abduct young women. The family travel from city to city leaving clues behind, but their route becomes increasingly difficult to follow.
The body of a young woman is found at a vineyard in the Napa Valley. Teresa thinks that the murder is the result of an argument between lovers, but Patrick suspects a serial kidnapper.
Jax, Clay and the boys deliver the first shipment of weapons to the Galindo cartel while Gemma forms an unlikely alliance in Charming.