An edgy janitor takes Clark's high-school class hostage at LuthorCorp, claiming his jitters were caused by a mysterious contaminant.
Attempting to stabilise Reed's powers, Caitlin and Lauren meet with Dr Risman, a doctor for those with debilitating X genes. However, Dr Risman is not who Lauren thought she was.
Tensions within the Inner Circle are at an all-time high. Lauren convinces Reed and Caitlin that they must take action to destroy Dr Risman's research.
When Junior is kidnapped as leverage to retrieve the stolen list of undercover CIA agents, Tani and Quinn ask Magnum and Higgins for their help.