When homeless people start disappearing, the team finds itself on the trail of a killer on a moral mission.
The team deal with a patient who suffers from recurring strokes, and as House prepares for his date with Cameron, the team offer advice.
While investigating the murder of a mental hospital patient and quickly narrowing down the suspects, the investigation takes a dangerous turn when Sara finds herself in a life-threatening situation.
Grace and the team investigate the shocking case of a man who killed his wife and then set his six-year-old son on fire. Meanwhile, Ham tries to cope with the loss of his brother, and Bobby goes undercover.