Derek and the attendings go out to celebrate when he gets the grant he needs for his clinical trial; Meredith and Alex must fend for themselves during the night shift.
The Behavioural Analysis Unit is called in on a Denver case where a home invasion led to the slaughter of an entire family.
Melinda comes across a young girl who shares the same ability as her and later discovers that Gabriel has been trying to lead other ghost whisperers to Grandview.
Martin is wracked with guilt after failing to prevent a 12-year-old boy from being dragged into a car outside the boy's school, but the team tries to ease Martin's anguish. Martin is also annoyed by Samantha's reluctance to tell their colleagues about their relationship.