As the storm rages, patients are brought to the hospital by the busload and resources dwindle; a doctor's life hangs in the balance.
A gas tanker explodes on a highway, resulting in multiple injuries; Jo and Meredith try to help a frantic woman, whose child has a mysterious illness; Alex is forced to work with Jo's boyfriend.
After several of Bailey's patients die, she becomes the focus of a CDC investigation; Cristina teases Alex about his feelings for Jo; Owen continues to take care of Ethan while his parents remain in the hospital.
The doctors prepare for a superstorm headed for Seattle; as Owen becomes closer to Ethan, his desire to be a parent gets stronger; Meredith and her baby are put in danger.
Unsettling news motivates Derek and Meredith to take preventive steps for their children's future; Syrian doctors come to the hospital for a crash course in basic surgical skills; April decides to tell Matthew the truth.
