Robin is admitted back into the hospital with more complications. Rhodes faces competition from a new hotshot doctor.
The shooting of Dr Charles moves to the courtroom. Dr Halsted and Dr Manning work on a heart-wrenching case.
Gorsch continues his reign of terror at Firehouse 51, while Brett and Foster respond to a call where a Halloween prank has turned deadly serious.
Dr Manning goes to extreme measures to help a fearful pregnant woman and Dr Choi and April try to strike a balance at work. Also, Dr Charles and Dr Reese continue to disagree about their patients.
When Goodwin receives financial complaints from the hospital board, she is forced to implement new guidelines that cause headaches for the doctors.