A religious sect member capable of changing gender becomes the prime suspect in a murder spree.
The agents face their old foe, Alex Krycek, while pursuing a radioactive entity unleashed from a sunken WWII wreckage.
Tony locks horns with a cop over his treatment of criminals, then clashes with a city efficiency expert.
Angie takes an aggressive approach to solve the murder of a high school student, 18-year-old high senior Emily Williams. Meanwhile, Lucas and Sung's relationship gets very personal.
MacGyver becomes the pawn in a Soviet scheme to steal a priceless Chinese national treasure, the Ming Dragon.