Damon focuses on holding himself together after an unexpected tragedy; Markos leaves Sheriff Forbes horrified; Bonnie seizes an opportunity to settle a score.
Elena struggles to cope with Damon's death as she returns to Whitmore College for her sophomore year. Luke gives her drugs in order to see Damon, but she soon develops side effects that make her violent.
Damon tries to figure out how to make a disturbing confession to Elena, Caroline discovers a frightening secret and Elena hangs out with mysterious fellow student Luke on the deserted college campus during spring break.
Enzo and Caroline go on a trip and find another doppleganger; Elena and Damon learn about Jeremy's bad behaviour at school; Bonnie has an encounter with Luke that leaves her unsettled.
Nadia remembers the centuries she spent searching for her mother; Matt, Stefan and Caroline try desperately to save Elena; Bonnie uncovers a terrifying secret that puts her friends at risk.
