Meredith struggles to balance her roles as a surgeon and a mother when she returns to work; Stephanie tries to impress Jackson's mother; Jo becomes overly involved with a patient.
The unit investigates an urban vampire in New York who kidnaps his victims at night and holds them underground in the sewer system.
The guys are stranded in the middle of nowhere when Leonard's car is stolen on the way to the Bakersfield Comic-Con. Back home, the women try to figure out why the guys are so fascinated with comic books.
When floating bodies turn up, Coulson and the agents must hunt down an elusive killer. Nobody is safe; not even the team.
In this episode, after the Machine gives out her social security number, Reese protects a journalist set on exposing the head of a group of corrupt cops. But her story is fatally flawed.