Dr Rhodes takes on a tricky case with a familiar patient, and Dr Halstead must decide whether to gamble on a young musician's hearing by performing surgery.
Kane's moves with the housing project escalate the situation from a state of unrest to rioting and looting. As Chicago burns, Kane secretly seeks treatment at an alternative clinic, where his past haunts him.
Kane keeps the city from bankruptcy by forming alliances with long-time enemies on the council, but he must decide whether he is prepared to make more serious concessions that could weaken his political machine.