On his first day as an intern, an idealistic Dr Devon Pravesh faces the harsh realities of medical care. Resident Conrad Hawkins teaches him unconventional methods for treating patients.
Conrad receives the call he's been waiting for when a heart becomes available for a patient who has been on the transplant list for two years. After a file goes missing, Nic grows suspicious of one of the doctors.
When Padma's pregnancy takes a dangerous turn, the doctors come together to find a solution and turn to Ian to perform a miracle; Conrad makes a decision regarding his love life and Devon leads his own clinical trials at Chastain.
An old army buddy and fellow surgeon visits Conrad at the hospital. Meanwhile, the team is put to the test when they have to save the life of an uninsured and undocumented patient.
After a mix-up in the Emergency Room causes Conrad to deliver a death notification to the wrong family, he sets out to fix it. Nic struggles to find the records of a patient under Lane's care.