The residents agonize over their upcoming exam results; Arizona's childhood friend needs medical help; the doctors try to help a patient missing one third of his skull; Julia wants to start a family with Mark.
The residents travel to San Francisco for the oral boards; sparks fly when Richard and Catherine (Debbie Allen) bump into each other at a hotel; Alex feels guilty.
The team must help an injured former Secret Service agent regain his memory in order to stop the launching of weapons of mass destruction.
The team investigates a series of home invasions involving casualties in upscale San Diego neighbourhoods.
After rescuing a woman, a subway hero collapses. House is unable to determine the man's illness. Meanwhile, Cuddy's mother visits and Taub's wife's libido is aroused.